Ex vivo mammalian prions are formed of paired double helical prion protein fibrils

Mammalian prions are hypothesized to be fibrillar or amyloid forms of prion protein (PrP), but structures observed to date have not been definitively correlated with infectivity and the three-dimensional structure of infectious prions has remained obscure. Recently, we developed novel methods to obt...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Open Biol
Päätekijät: Terry, Cassandra, Wenborn, Adam, Gros, Nathalie, Sells, Jessica, Joiner, Susan, Hosszu, Laszlo L. P., Tattum, M. Howard, Panico, Silvia, Clare, Daniel K., Collinge, John, Saibil, Helen R., Wadsworth, Jonathan D. F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Royal Society 2016
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892434/
https://ncbi.nlm.nih.gov/pubmed/27249641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160035
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