A novel and rapid method for obtaining high titre intact prion strains from mammalian brain

Mammalian prions exist as multiple strains which produce characteristic and highly reproducible phenotypes in defined hosts. How this strain diversity is encoded by a protein-only agent remains one of the most interesting and challenging questions in biology with wide relevance to understanding othe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wenborn, Adam, Terry, Cassandra, Gros, Nathalie, Joiner, Susan, D’Castro, Laura, Panico, Silvia, Sells, Jessica, Cronier, Sabrina, Linehan, Jacqueline M., Brandner, Sebastian, Saibil, Helen R., Collinge, John, Wadsworth, Jonathan D. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423448/
https://ncbi.nlm.nih.gov/pubmed/25950908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10062
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