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A novel and rapid method for obtaining high titre intact prion strains from mammalian brain

Mammalian prions exist as multiple strains which produce characteristic and highly reproducible phenotypes in defined hosts. How this strain diversity is encoded by a protein-only agent remains one of the most interesting and challenging questions in biology with wide relevance to understanding othe...

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發表在:Sci Rep
Main Authors: Wenborn, Adam, Terry, Cassandra, Gros, Nathalie, Joiner, Susan, D’Castro, Laura, Panico, Silvia, Sells, Jessica, Cronier, Sabrina, Linehan, Jacqueline M., Brandner, Sebastian, Saibil, Helen R., Collinge, John, Wadsworth, Jonathan D. F.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423448/
https://ncbi.nlm.nih.gov/pubmed/25950908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10062
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