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Spontaneous generation of mammalian prions

Prions are transmissible agents that cause lethal neurodegeneration in humans and other mammals. Prions bind avidly to metal surfaces such as steel wires and, when surface-bound, can initiate infection of brain or cultured cells with remarkable efficiency. While investigating the properties of metal...

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Autors principals: Edgeworth, Julie A., Gros, Nathalie, Alden, Jack, Joiner, Susan, Wadsworth, Jonathan D. F., Linehan, Jackie, Brandner, Sebastian, Jackson, Graham S., Weissmann, Charles, Collinge, John
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922516/
https://ncbi.nlm.nih.gov/pubmed/20660771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004036107
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