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Spontaneous generation of mammalian prions

Prions are transmissible agents that cause lethal neurodegeneration in humans and other mammals. Prions bind avidly to metal surfaces such as steel wires and, when surface-bound, can initiate infection of brain or cultured cells with remarkable efficiency. While investigating the properties of metal...

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Detalhes bibliográficos
Main Authors: Edgeworth, Julie A., Gros, Nathalie, Alden, Jack, Joiner, Susan, Wadsworth, Jonathan D. F., Linehan, Jackie, Brandner, Sebastian, Jackson, Graham S., Weissmann, Charles, Collinge, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922516/
https://ncbi.nlm.nih.gov/pubmed/20660771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004036107
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