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RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications

Accurate genetic information transfer is essential for life. As a key enzyme involved in the first step of gene expression, RNA polymerase II (Pol II) must maintain high transcriptional fidelity while it reads along DNA template and synthesizes RNA transcript in a stepwise manner during transcriptio...

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Bibliographic Details
Published in:Crit Rev Biochem Mol Biol
Main Authors: Xu, Liang, Wang, Wei, Chong, Jenny, Shin, Ji Hyun, Xu, Jun, Wang, Dong
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891981/
https://ncbi.nlm.nih.gov/pubmed/26392149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2015.1087960
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