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Dissecting Chemical Interactions Governing RNA Polymerase II Transcriptional Fidelity
Maintaining high transcriptional fidelity is essential to life. For all eukaryotic organisms, RNA polymerase II (Pol II) is responsible for messenger RNA synthesis from the DNA template. Three key checkpoint steps are important in controlling Pol II transcriptional fidelity: nucleotide selection and...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367139/ https://ncbi.nlm.nih.gov/pubmed/22509745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja302077d |
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