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Dissecting Chemical Interactions Governing RNA Polymerase II Transcriptional Fidelity

Maintaining high transcriptional fidelity is essential to life. For all eukaryotic organisms, RNA polymerase II (Pol II) is responsible for messenger RNA synthesis from the DNA template. Three key checkpoint steps are important in controlling Pol II transcriptional fidelity: nucleotide selection and...

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Detalhes bibliográficos
Main Authors: Kellinger, Matthew W., Ulrich, Sébastien, Chong, Jenny, Kool, Eric T., Wang, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367139/
https://ncbi.nlm.nih.gov/pubmed/22509745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja302077d
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