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The Importance of Steric Effects on the Efficiency and Fidelity of Transcription by T7 RNA Polymerase
DNA-dependent RNA polymerases such as T7 RNA polymerase perform the transcription of DNA into mRNA with high efficiency and high fidelity. Although structural studies have provided a detailed account of the molecular basis of transcription, the relative importance of factors like hydrogen bonds and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222776/ https://ncbi.nlm.nih.gov/pubmed/22044042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2011465 |
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