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Effect of carcinogenic adducts on transcription by T7 RNA polymerase.

The effect of modifying the T7 promoter-containing plasmid pDR100 with aminofluorene (AF), acetylaminofluorene (AAF), and benzo[a]pyrene (B[a]P) adducts on RNA synthesis by the T7 RNA polymerase was determined. We found that increasing levels of each of the three adducts caused a progressive decline...

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Main Authors: Nath, S T, Lee, M S, Romano, L J
格式: Artigo
語言:Inglês
出版: 1987
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC340846/
https://ncbi.nlm.nih.gov/pubmed/3588293
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