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Effect of carcinogenic adducts on transcription by T7 RNA polymerase.
The effect of modifying the T7 promoter-containing plasmid pDR100 with aminofluorene (AF), acetylaminofluorene (AAF), and benzo[a]pyrene (B[a]P) adducts on RNA synthesis by the T7 RNA polymerase was determined. We found that increasing levels of each of the three adducts caused a progressive decline...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1987
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC340846/ https://ncbi.nlm.nih.gov/pubmed/3588293 |
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