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DNA Polymerase: Structural Homology, Conformational Dynamics, and the Effects of Carcinogenic DNA Adducts

DNA replication is vital for an organism to proliferate and lying at the heart of this process is the enzyme DNA polymerase. Most DNA polymerases have a similar three dimensional fold, akin to a human right hand, despite differences in sequence homology. This structural homology would predict a rela...

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Detalhes bibliográficos
Main Authors: Federley, Richard G., Romano, Louis J.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933918/
https://ncbi.nlm.nih.gov/pubmed/20847947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/457176
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