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Studies on the conformation and dynamics of the C8-substituted guanine adduct of the carcinogen acetylaminofluorene; model for a possible Z-DNA modified structure.

The structure of an adduct between guanine and the carcinogen acetylaminofluorene has been examined in the solid state by X-ray crystallography, and in solution by NMR techniques. The observed conformations have been compared with predictions from energy calculations and their relevance to models of...

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Detalhes bibliográficos
Main Authors: Neidle, S, Kuroda, R, Broyde, S, Hingerty, B E, Levine, R A, Miller, D W, Evans, F E
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC320303/
https://ncbi.nlm.nih.gov/pubmed/6504698
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