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Epigenetic DNA Modification N(6)-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing
N (6)-Methyladenine (N(6)-mA or 6 mA) is an epigenetic DNA modification in eukaryotic genomes. In contrast to the well-established roles of 5-methylcytosine for epigenetic regulation of gene expression, the functional roles of N(6)-mA remain elusive. In particular, the impact of N(6)-mA modification...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5812728/ https://ncbi.nlm.nih.gov/pubmed/28933854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b06381 |
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