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Pause Sites Promote Transcriptional Termination of Mammalian RNA Polymerase II

Polymerase II (Pol II) transcriptional termination depends on two independent genetic elements: poly(A) signals and downstream terminator sequences. The latter may either promote cotranscriptional RNA cleavage or pause elongating Pol II. We demonstrate that the previously characterized MAZ(4) pause...

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Detalhes bibliográficos
Main Authors: Gromak, Natalia, West, Steven, Proudfoot, Nick J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1488997/
https://ncbi.nlm.nih.gov/pubmed/16648491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.10.3986-3996.2006
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