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Molecular Dissection of Mammalian RNA Polymerase II Transcriptional Termination

Transcriptional termination of mammalian RNA polymerase II (Pol II) is an essential but little-understood step in protein-coding gene expression. Mechanistically, termination by all DNA-dependent RNA polymerases can be reduced to two steps, namely release of the RNA transcript and release of the DNA...

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Autori principali: West, Steven, Proudfoot, Nicholas J., Dye, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288634/
https://ncbi.nlm.nih.gov/pubmed/18342606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.12.019
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