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Transcriptional termination in mammals: Stopping the RNA polymerase II juggernaut

Terminating transcription is a highly intricate process for mammalian protein-coding genes. First, the chromatin template slows down transcription at the gene end. Then, the transcript is cleaved at the poly(A) signal to release the messenger RNA.The remaining transcript is selectively unraveled and...

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Bibliografske podrobnosti
izdano v:Science
Glavni avtor: Proudfoot, Nick J.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144996/
https://ncbi.nlm.nih.gov/pubmed/27284201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad9926
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