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Discovery of prenylated flavonoids with dual activity against influenza virus and Streptococcus pneumoniae

Influenza virus neuraminidase (NA) is the primary target for influenza therapeutics. Severe complications are often related to secondary pneumonia caused by Streptococcus pneumoniae (pneumococci), which also express NAs. Recently, a NA-mediated lethal synergism between influenza A viruses and pneumo...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Grienke, Ulrike, Richter, Martina, Walther, Elisabeth, Hoffmann, Anja, Kirchmair, Johannes, Makarov, Vadim, Nietzsche, Sandor, Schmidtke, Michaela, Rollinger, Judith M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891693/
https://ncbi.nlm.nih.gov/pubmed/27257160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27156
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