Pyrazolopyrimidines: Potent Inhibitors Targeting the Capsid of Rhino- and Enteroviruses

There are currently no drugs available for the treatment of enterovirus (EV)-induced acute and chronic diseases such as the common cold, meningitis, encephalitis, pneumonia, and myocarditis with or without consecutive dilated cardiomyopathy. Here, we report the discovery and characterization of pyra...

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Bibliographic Details
Published in:ChemMedChem
Main Authors: Makarov, Vadim A, Braun, Heike, Richter, Martina, Riabova, Olga B, Kirchmair, Johannes, Kazakova, Elena S, Seidel, Nora, Wutzler, Peter, Schmidtke, Michaela
Format: Artigo
Language:Inglês
Published: WILEY-VCH Verlag 2015
Subjects:
Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600222/
https://ncbi.nlm.nih.gov/pubmed/26260222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500304
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