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A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses
Rhino- and enteroviruses are important human pathogens, against which no antivirals are available. The best-studied inhibitors are “capsid binders” that fit in a hydrophobic pocket of the viral capsid. Employing a new class of entero-/rhinovirus inhibitors and by means of cryo–electron microscopy (E...
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| Yayımlandı: | PLoS Biol |
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| Asıl Yazarlar: | , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6559632/ https://ncbi.nlm.nih.gov/pubmed/31185007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000281 |
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