Computer-Guided Approach to Access the Anti-influenza Activity of Licorice Constituents

[Image: see text] Neuraminidase (NA), a key enzyme in viral replication, is the first-line drug target to combat influenza. On the basis of a shape-focused virtual screening, the roots of Glycyrrhiza glabra (licorice) were identified as plant species with an accumulation of constituents that show 3D...

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Detalhes bibliográficos
Main Authors: Grienke, Ulrike, Braun, Heike, Seidel, Nora, Kirchmair, Johannes, Richter, Martina, Krumbholz, Andi, von Grafenstein, Susanne, Liedl, Klaus R., Schmidtke, Michaela, Rollinger, Judith M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society and American Society of Pharmacognosy 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971757/
https://ncbi.nlm.nih.gov/pubmed/24313801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400817j
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