Discovery and Characterization of Diazenylaryl Sulfonic Acids as Inhibitors of Viral and Bacterial Neuraminidases

Viral neuraminidases are an established drug target to combat influenza. Severe complications observed in influenza patients are primarily caused by secondary infections with e.g., Streptococcus pneumoniae. These bacteria engage in a lethal synergism with influenza A viruses (IAVs) and also express...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Hoffmann, Anja, Richter, Martina, von Grafenstein, Susanne, Walther, Elisabeth, Xu, Zhongli, Schumann, Lilia, Grienke, Ulrike, Mair, Christina E., Kramer, Christian, Rollinger, Judith M., Liedl, Klaus R., Schmidtke, Michaela, Kirchmair, Johannes
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309245/
https://ncbi.nlm.nih.gov/pubmed/28261167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00205
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