Discovery and Characterization of Diazenylaryl Sulfonic Acids as Inhibitors of Viral and Bacterial Neuraminidases

Viral neuraminidases are an established drug target to combat influenza. Severe complications observed in influenza patients are primarily caused by secondary infections with e.g., Streptococcus pneumoniae. These bacteria engage in a lethal synergism with influenza A viruses (IAVs) and also express...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Hoffmann, Anja, Richter, Martina, von Grafenstein, Susanne, Walther, Elisabeth, Xu, Zhongli, Schumann, Lilia, Grienke, Ulrike, Mair, Christina E., Kramer, Christian, Rollinger, Judith M., Liedl, Klaus R., Schmidtke, Michaela, Kirchmair, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309245/
https://ncbi.nlm.nih.gov/pubmed/28261167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00205
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