Discovery and Characterization of Diazenylaryl Sulfonic Acids as Inhibitors of Viral and Bacterial Neuraminidases

Viral neuraminidases are an established drug target to combat influenza. Severe complications observed in influenza patients are primarily caused by secondary infections with e.g., Streptococcus pneumoniae. These bacteria engage in a lethal synergism with influenza A viruses (IAVs) and also express...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Autores principales: Hoffmann, Anja, Richter, Martina, von Grafenstein, Susanne, Walther, Elisabeth, Xu, Zhongli, Schumann, Lilia, Grienke, Ulrike, Mair, Christina E., Kramer, Christian, Rollinger, Judith M., Liedl, Klaus R., Schmidtke, Michaela, Kirchmair, Johannes
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309245/
https://ncbi.nlm.nih.gov/pubmed/28261167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00205
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