Dual Acting Neuraminidase Inhibitors Open New Opportunities to Disrupt the Lethal Synergism between Streptococcus pneumoniae and Influenza Virus

Secondary infections with Streptococcus pneumoniae cause severe pneumonia and enhance lethality during influenza epidemics and pandemics. Structural and functional similarities with viral neuraminidase (NA) suggest that the highly prevalent pneumococcal NAs, NanA and NanB, might contribute to this l...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Walther, Elisabeth, Xu, Zhongli, Richter, Martina, Kirchmair, Johannes, Grienke, Ulrike, Rollinger, Judith M., Krumbholz, Andi, Saluz, Hans P., Pfister, Wolfgang, Sauerbrei, Andreas, Schmidtke, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800182/
https://ncbi.nlm.nih.gov/pubmed/27047471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00357
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