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Herpes Simplex Virus 1 Serine Protease VP24 Blocks the DNA-Sensing Signal Pathway by Abrogating Activation of Interferon Regulatory Factor 3
The interferon (IFN)-mediated antiviral response is a central aspect of host defense; however, viruses have evolved multiple strategies to counteract IFN-mediated responses in order to successfully infect the host. Herpes simplex virus 1 (HSV-1), a typical human-restricted DNA virus, is capable of c...
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Publicado en: | J Virol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
American Society for Microbiology
2016
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886774/ https://ncbi.nlm.nih.gov/pubmed/27076640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00186-16 |
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