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Herpes Simplex Virus 1 Ubiquitin-Specific Protease UL36 Abrogates NF-κB Activation in DNA Sensing Signal Pathway

The DNA sensing pathway triggers innate immune responses against DNA virus infection, and NF-κB signaling plays a critical role in establishing innate immunity. We report here that the herpes simplex virus 1 (HSV-1) ubiquitin-specific protease (UL36USP), which is a deubiquitinase (DUB), antagonizes...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Ye, Ruijie, Su, Chenhe, Xu, Haiyan, Zheng, Chunfu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309955/
https://ncbi.nlm.nih.gov/pubmed/28031360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02417-16
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