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Herpes simplex virus 1 UL41 protein abrogates the antiviral activity of hZAP by degrading its mRNA

BACKGROUND: The zinc finger antiviral protein (ZAP) is a host restriction factor that inhibits the replication of various viruses by degradation of certain viral mRNA. However, previous study demonstrated that ectopic expression of rat ZAP did not suppress the replication of herpes simplex virus typ...

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Bibliographische Detailangaben
Veröffentlicht in:Virol J
Hauptverfasser: Su, Chenhe, Zhang, Jie, Zheng, Chunfu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666169/
https://ncbi.nlm.nih.gov/pubmed/26625984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0433-y
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