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Herpes Simplex Virus 1 Tegument Protein VP22 Abrogates cGAS/STING-Mediated Antiviral Innate Immunity

Cytosolic DNA arising from intracellular pathogens is sensed by cyclic GMP-AMP synthase (cGAS) and triggers a powerful innate immune response. However, herpes simplex virus 1 (HSV-1), a double-stranded DNA virus, has developed multiple mechanisms to attenuate host antiviral machinery and facilitate...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Huang, Jian, You, Hongjuan, Su, Chenhe, Li, Yangxin, Chen, Shunhua, Zheng, Chunfu
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052299/
https://ncbi.nlm.nih.gov/pubmed/29793952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00841-18
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