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Herpes Simplex Virus 1 Ubiquitin-Specific Protease UL36 Inhibits Beta Interferon Production by Deubiquitinating TRAF3

Interferon (IFN)-mediated innate immune defense is a potent antiviral mechanism. Viruses evade innate immunity and limit secretion of beta interferon (IFN-β) to replicate and survive in the host. The largest tegument protein of herpes simplex virus 1 (HSV-1), UL36, contains a novel deubiquitinase (D...

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Detalhes bibliográficos
Main Authors: Wang, Shuai, Wang, Kezhen, Li, Jie, Zheng, Chunfu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807349/
https://ncbi.nlm.nih.gov/pubmed/23986588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01211-13
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