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Herpes Simplex Virus 1 Serine/Threonine Kinase US3 Hyperphosphorylates IRF3 and Inhibits Beta Interferon Production

Viral infection initiates a series of signaling cascades that lead to the transcription of interferons (IFNs), finally inducing interferon-stimulated genes (ISGs) to eliminate viruses. Viruses have evolved a variety of strategies to modulate host IFN-mediated immune responses. Herpes simplex virus 1...

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Detalhes bibliográficos
Main Authors: Wang, Shuai, Wang, Kezhen, Lin, Rongtuan, Zheng, Chunfu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838156/
https://ncbi.nlm.nih.gov/pubmed/24049179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02355-13
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