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Herpes Simplex Virus 1 Serine Protease VP24 Blocks the DNA-Sensing Signal Pathway by Abrogating Activation of Interferon Regulatory Factor 3

The interferon (IFN)-mediated antiviral response is a central aspect of host defense; however, viruses have evolved multiple strategies to counteract IFN-mediated responses in order to successfully infect the host. Herpes simplex virus 1 (HSV-1), a typical human-restricted DNA virus, is capable of c...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zhang, Dandan, Su, Chenhe, Zheng, Chunfu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886774/
https://ncbi.nlm.nih.gov/pubmed/27076640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00186-16
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