PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells

Pancreatic adenocarcinoma is currently the fourth leading cause for cancer-related mortality. Malignant progression of pancreatic cancer depends not only on rapid proliferation of tumor cells but also on increased cell motility. In this study, we showed that increased PHLPP expression significantly...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Smith, Alena J., Wen, Yang-An, Stevens, Payton D., Liu, Jingpeng, Wang, Chi, Gao, Tianyan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884955/
https://ncbi.nlm.nih.gov/pubmed/26760962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6848
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