PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells

Pancreatic adenocarcinoma is currently the fourth leading cause for cancer-related mortality. Malignant progression of pancreatic cancer depends not only on rapid proliferation of tumor cells but also on increased cell motility. In this study, we showed that increased PHLPP expression significantly...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Smith, Alena J., Wen, Yang-An, Stevens, Payton D., Liu, Jingpeng, Wang, Chi, Gao, Tianyan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884955/
https://ncbi.nlm.nih.gov/pubmed/26760962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6848
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