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PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells

Pancreatic adenocarcinoma is currently the fourth leading cause for cancer-related mortality. Malignant progression of pancreatic cancer depends not only on rapid proliferation of tumor cells but also on increased cell motility. In this study, we showed that increased PHLPP expression significantly...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Smith, Alena J., Wen, Yang-An, Stevens, Payton D., Liu, Jingpeng, Wang, Chi, Gao, Tianyan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884955/
https://ncbi.nlm.nih.gov/pubmed/26760962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6848
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