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Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors

Breast cancer is one of the leading causes of death worldwide, and therefore, new and improved approaches for the treatment of breast cancer are desperately needed. CtIP (RBBP8) is a multifunctional protein that is involved in various cellular functions, including transcription, DNA replication, DNA...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Wang, Junhui, Ding, Qianshan, Fujimori, Hiroaki, Motegi, Akira, Miki, Yoshio, Masutani, Mitsuko
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884948/
https://ncbi.nlm.nih.gov/pubmed/26713604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6715
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