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Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors

Breast cancer is one of the leading causes of death worldwide, and therefore, new and improved approaches for the treatment of breast cancer are desperately needed. CtIP (RBBP8) is a multifunctional protein that is involved in various cellular functions, including transcription, DNA replication, DNA...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Wang, Junhui, Ding, Qianshan, Fujimori, Hiroaki, Motegi, Akira, Miki, Yoshio, Masutani, Mitsuko
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884948/
https://ncbi.nlm.nih.gov/pubmed/26713604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6715
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