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When two is not enough: a CtIP tetramer is required for DNA repair by Homologous Recombination

Homologous recombination (HR) is central to the repair of double-strand DNA breaks that occur in S/G2 phases of the cell cycle. HR relies on the CtIP protein (Ctp1 in fission yeast, Sae2 in budding yeast) for resection of DNA ends, a key step in generating the 3′-DNA overhangs that are required for...

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Библиографические подробности
Опубликовано в: :Nucleus
Главные авторы: Forment, Josep V, Jackson, Stephen P, Pellegrini, Luca
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915501/
https://ncbi.nlm.nih.gov/pubmed/26305173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2015.1086050
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