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When two is not enough: a CtIP tetramer is required for DNA repair by Homologous Recombination
Homologous recombination (HR) is central to the repair of double-strand DNA breaks that occur in S/G2 phases of the cell cycle. HR relies on the CtIP protein (Ctp1 in fission yeast, Sae2 in budding yeast) for resection of DNA ends, a key step in generating the 3′-DNA overhangs that are required for...
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| Опубликовано в: : | Nucleus |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4915501/ https://ncbi.nlm.nih.gov/pubmed/26305173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2015.1086050 |
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