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Peptides Comprised of Alternating L- and D- Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of Sequence

There is now substantial evidence that soluble oligomers are primary toxic agents in amyloid diseases. Development of an antibody recognizing the toxic soluble oligomeric forms of different and unrelated amyloid species suggests a common conformational intermediate during amyloidogenesis. We previou...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Mol Biol
मुख्य लेखकों: Kellock, Jackson, Hopping, Gene, Caughey, Byron, Daggett, Valerie
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884539/
https://ncbi.nlm.nih.gov/pubmed/27012425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.03.013
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