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Peptides Comprised of Alternating L- and D- Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of Sequence
There is now substantial evidence that soluble oligomers are primary toxic agents in amyloid diseases. Development of an antibody recognizing the toxic soluble oligomeric forms of different and unrelated amyloid species suggests a common conformational intermediate during amyloidogenesis. We previou...
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| 出版年: | J Mol Biol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4884539/ https://ncbi.nlm.nih.gov/pubmed/27012425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.03.013 |
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