Analysis of Jak2 signaling reveals resistance of mouse embryonic hematopoietic stem cells to myeloproliferative disease mutation

The regulation of hematopoietic stem cell (HSC) emergence during development provides important information about the basic mechanisms of blood stem cell generation, expansion, and migration. We set out to investigate the role that cytokine signaling pathways play in these early processes and show h...

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Bibliographic Details
Published in:Blood
Main Authors: Mascarenhas, Maria I., Bacon, Wendi A., Kapeni, Chrysa, Fitch, Simon R., Kimber, Gillian, Cheng, S. W. Priscilla, Li, Juan, Green, Anthony R., Ottersbach, Katrin
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2016
Subjects:
Hematopoiesis and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882783/
https://ncbi.nlm.nih.gov/pubmed/26864339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-08-664631
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