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Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling

The first adult-repopulating hematopoietic stem cells (HSCs) are detected starting at day 10.5 of gestation in the aorta-gonads-mesonephros (AGM) region of the mouse embryo. Despite the importance of the AGM in initiating HSC production, very little is currently known about the regulators that contr...

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Detalhes bibliográficos
Main Authors: Mascarenhas, Maria I., Parker, Aimée, Dzierzak, Elaine, Ottersbach, Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780301/
https://ncbi.nlm.nih.gov/pubmed/19794138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-06-230037
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