Analysis of Jak2 signaling reveals resistance of mouse embryonic hematopoietic stem cells to myeloproliferative disease mutation

The regulation of hematopoietic stem cell (HSC) emergence during development provides important information about the basic mechanisms of blood stem cell generation, expansion, and migration. We set out to investigate the role that cytokine signaling pathways play in these early processes and show h...

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Publicat a:Blood
Autors principals: Mascarenhas, Maria I., Bacon, Wendi A., Kapeni, Chrysa, Fitch, Simon R., Kimber, Gillian, Cheng, S. W. Priscilla, Li, Juan, Green, Anthony R., Ottersbach, Katrin
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2016
Matèries:
Hematopoiesis and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882783/
https://ncbi.nlm.nih.gov/pubmed/26864339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-08-664631
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