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Analysis of Jak2 signaling reveals resistance of mouse embryonic hematopoietic stem cells to myeloproliferative disease mutation

The regulation of hematopoietic stem cell (HSC) emergence during development provides important information about the basic mechanisms of blood stem cell generation, expansion, and migration. We set out to investigate the role that cytokine signaling pathways play in these early processes and show h...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Mascarenhas, Maria I., Bacon, Wendi A., Kapeni, Chrysa, Fitch, Simon R., Kimber, Gillian, Cheng, S. W. Priscilla, Li, Juan, Green, Anthony R., Ottersbach, Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882783/
https://ncbi.nlm.nih.gov/pubmed/26864339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-08-664631
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