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Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells
Hematopoietic stem cell (HSC) self-renewal and differentiation is regulated by cellular and molecular interactions with the surrounding microenvironment. During ontogeny, the aorta–gonad–mesonephros (AGM) region autonomously generates the first HSCs and serves as the first HSC-supportive microenviro...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409228/ https://ncbi.nlm.nih.gov/pubmed/18087045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706923105 |
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