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Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells

Hematopoietic stem cell (HSC) self-renewal and differentiation is regulated by cellular and molecular interactions with the surrounding microenvironment. During ontogeny, the aorta–gonad–mesonephros (AGM) region autonomously generates the first HSCs and serves as the first HSC-supportive microenviro...

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Bibliografski detalji
Glavni autori: Durand, Charles, Robin, Catherine, Bollerot, Karine, Baron, Margaret H., Ottersbach, Katrin, Dzierzak, Elaine
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409228/
https://ncbi.nlm.nih.gov/pubmed/18087045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706923105
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