Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells

Hematopoietic stem cell (HSC) self-renewal and differentiation is regulated by cellular and molecular interactions with the surrounding microenvironment. During ontogeny, the aorta–gonad–mesonephros (AGM) region autonomously generates the first HSCs and serves as the first HSC-supportive microenviro...

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Autors principals: Durand, Charles, Robin, Catherine, Bollerot, Karine, Baron, Margaret H., Ottersbach, Katrin, Dzierzak, Elaine
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409228/
https://ncbi.nlm.nih.gov/pubmed/18087045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706923105
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