Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development

Hematopoiesis is initiated in several distinct tissues in the mouse conceptus. The aorta-gonad-mesonephros (AGM) region is of particular interest, as it autonomously generates the first adult type hematopoietic stem cells (HSCs). The ventral position of hematopoietic clusters closely associated with...

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Bibliografiske detaljer
Main Authors: Peeters, Marian, Ottersbach, Katrin, Bollerot, Karine, Orelio, Claudia, de Bruijn, Marella, Wijgerde, Mark, Dzierzak, Elaine
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2009
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709067/
https://ncbi.nlm.nih.gov/pubmed/19570846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.034728
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