BMP and Hedgehog Regulate Distinct AGM Hematopoietic Stem Cells Ex Vivo

Hematopoietic stem cells (HSC), the self-renewing cells of the adult blood differentiation hierarchy, are generated during embryonic stages. The first HSCs are produced in the aorta-gonad-mesonephros (AGM) region of the embryo through endothelial to a hematopoietic transition. BMP4 and Hedgehog affe...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Stem Cell Reports
Päätekijät: Crisan, Mihaela, Solaimani Kartalaei, Parham, Neagu, Alex, Karkanpouna, Sofia, Yamada-Inagawa, Tomoko, Purini, Caterina, Vink, Chris S., van der Linden, Reinier, van Ijcken, Wilfred, Chuva de Sousa Lopes, Susana M., Monteiro, Rui, Mummery, Christine, Dzierzak, Elaine
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788785/
https://ncbi.nlm.nih.gov/pubmed/26923823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.01.016
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