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BMP and Hedgehog Regulate Distinct AGM Hematopoietic Stem Cells Ex Vivo
Hematopoietic stem cells (HSC), the self-renewing cells of the adult blood differentiation hierarchy, are generated during embryonic stages. The first HSCs are produced in the aorta-gonad-mesonephros (AGM) region of the embryo through endothelial to a hematopoietic transition. BMP4 and Hedgehog affe...
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| Publicado no: | Stem Cell Reports |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4788785/ https://ncbi.nlm.nih.gov/pubmed/26923823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.01.016 |
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