HIF1α is a regulator of hematopoietic progenitor and stem cell development in hypoxic sites of the mouse embryo

Hypoxia affects many physiologic processes during early stages of mammalian ontogeny, particularly placental and vascular development. In the adult, the hypoxic bone marrow microenvironment plays a role in regulating hematopoietic stem cell (HSC) function. HSCs are generated from the major vasculatu...

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Autores principales: Imanirad, Parisa, Kartalaei, Parham Solaimani, Crisan, Mihaela, Vink, Chris, Yamada-Inagawa, Tomoko, de Pater, Emma, Kurek, Dorota, Kaimakis, Polynikis, van der Linden, Reiner, Speck, Nancy, Dzierzak, Elaine
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964602/
https://ncbi.nlm.nih.gov/pubmed/24141110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2013.09.006
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