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Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells

Hematopoietic stem cell (HSC) self-renewal and differentiation is regulated by cellular and molecular interactions with the surrounding microenvironment. During ontogeny, the aorta–gonad–mesonephros (AGM) region autonomously generates the first HSCs and serves as the first HSC-supportive microenviro...

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Detalhes bibliográficos
Main Authors: Durand, Charles, Robin, Catherine, Bollerot, Karine, Baron, Margaret H., Ottersbach, Katrin, Dzierzak, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409228/
https://ncbi.nlm.nih.gov/pubmed/18087045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706923105
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