The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease

COPD is characterized by persistent airflow limitation, neutrophilia and oxidative stress from endogenous and exogenous insults. Current COPD therapy involving anticholinergics, β(2)-adrenoceptor agonists and/or corticosteroids, do not specifically target oxidative stress, nor do they reduce chronic...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Han, Bing, Poppinga, Wilfred J., Zuo, Haoxiao, Zuidhof, Annet B., Bos, I. Sophie T., Smit, Marieke, Vogelaar, Pieter, Krenning, Guido, Henning, Robert H., Maarsingh, Harm, Halayko, Andrew J., van Vliet, Bernard, Stienstra, Stef, Graaf, Adrianus Cornelis van der, Meurs, Herman, Schmidt, Martina
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882609/
https://ncbi.nlm.nih.gov/pubmed/27229886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26928
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