Small airway hyperresponsiveness in COPD: relationship between structure and function in lung slices

The direct relationship between pulmonary structural changes and airway hyperresponsiveness (AHR) in chronic obstructive pulmonary disease (COPD) is unclear. We investigated AHR in relation to airway and parenchymal structural changes in a guinea pig model of COPD and in COPD patients. Precision-cut...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Maarsingh, Harm, Bidan, Cécile M., Brook, Bindi S., Zuidhof, Annet B., Elzinga, Carolina R.S., Smit, Marieke, Oldenburger, Anouk, Gosens, Reinoud, Timens, Wim, Meurs, Herman
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459292/
https://ncbi.nlm.nih.gov/pubmed/30628486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00325.2018
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