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Heparin normalizes allergen-induced nitric oxide deficiency and airway hyperresponsiveness

1. It has been established that polycations cause airway hyperresponsiveness (AHR) to methacholine by inducing a deficiency of constitutive nitric oxide synthase (cNOS)-derived bronchodilating nitric oxide (NO). Since a deficiency of cNOS-derived NO also contributes to allergen-induced AHR after the...

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Detalhes bibliográficos
Main Authors: Maarsingh, Harm, de Boer, Jacob, Kauffman, Henk F, Zaagsma, Johan, Meurs, Herman
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575183/
https://ncbi.nlm.nih.gov/pubmed/15265801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705848
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