Deficiency of nitric oxide in polycation-induced airway hyperreactivity

Using a perfused guinea-pig tracheal tube preparation, we investigated the role of endogenous nitric oxide (NO) in polycation-induced airway hyperreactivity (AHR) to methacholine. Intraluminal (IL) administration of the NO synthase inhibitor N(ω)-nitro-L-arginine methyl ester (L-NAME; 100 μM) caused...

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Detalles Bibliográficos
Main Authors: Meurs, Herman, Schuurman, Fineke E, Duyvendak, Michiel, Zaagsma, Johan
Formato: Artigo
Idioma:Inglês
Publicado: 1999
Assuntos:
Special Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565870/
https://ncbi.nlm.nih.gov/pubmed/10188962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702372
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