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Tumor Suppressor Folliculin Regulates mTORC1 through Primary Cilia
Folliculin (FLCN) is the tumor suppressor associated with Birt-Hogg-Dubé (BHD) syndrome that predisposes patients to incident of hamartomas and cysts in multiple organs. Its inactivation causes deregulation in the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway. However, the under...
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| 發表在: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4882437/ https://ncbi.nlm.nih.gov/pubmed/27072130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.719997 |
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